Treaty IV

Free

Treaty IV is a ready-to-use intravenous formulation of Paracetamol, delivering rapid onset analgesic and antipyretic action in hospitalized patients. Designed for controlled infusion, it provides effective relief from moderate pain and fever when oral or rectal administration is not feasible. The 1.0% w/v concentration ensures accurate dosing and better patient compliance in acute care settings.

Category:

Description

Key Benefits

  • Rapid fever reduction and pain control

  • Suitable for post-operative pain, trauma, or febrile conditions

  • Bypasses the gastrointestinal tract – ideal for NPO patients

  • Well-tolerated with minimal gastrointestinal or renal side effects compared to NSAIDs

  • Helps reduce opioid requirements in combination therapy


Dosage & Administration

  • Adults & Adolescents ≥50 kg: 1000 mg (100 mL) IV over 15 minutes

  • Children & Patients <50 kg: Dose based on body weight (15 mg/kg), not exceeding 1g per dose or 4g per day

  • Frequency: Every 6 hours, not exceeding 4 doses in 24 hours

  • Administration: IV infusion only – do not administer as a bolus or injection


Precautions & Warnings

  • Use with caution in patients with:

    • Liver dysfunction or chronic alcoholism

    • Dehydration or malnutrition

  • Monitor hepatic function during prolonged use

  • Do not exceed recommended dose – risk of hepatotoxicity

  • Pregnancy Category B – use only if clearly needed under medical supervision


Storage Instructions

  • Store below 25°C

  • Do not freeze

  • Use immediately after opening

  • Keep out of reach of children

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